NMDARS DRIVE THE EXPRESSION OF NEUROPSYCHIATRIC DISORDER RISK GENES WITHIN GABAERGIC INTERNEURON SUBTYPES IN THE JUVENILE BRAIN

NMDARs Drive the Expression of Neuropsychiatric Disorder Risk Genes Within GABAergic Interneuron Subtypes in the Juvenile Brain

Medial ganglionic eminence (MGE)-derived parvalbumin (PV)+, somatostatin (SST)+and Neurogliaform (NGFC)-type cortical and hippocampal interneurons, have distinct molecular, anatomical, and physiological properties.However, the molecular mechanisms regulating their maturation remain poorly understood.Here, via single-cell transcriptomics, Michigan w

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Evidence for eosinophil degranulation in acute appendicitis

Finding of increased numbers of eosinophils in the muscle in cases of acute appendicitis has led to the hypothesis that it may have an allergic origin.This study aimed to measure the eosinophil degranulation resulting in a rise in the serum of eosinophil granule proteins that would Glandulars be expected in such cases.The levels of serum eosinophil

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Trauma exposure, posttraumatic stress, and comorbidities in female adolescent offenders: findings and implications from recent studies

Background: While males constitute the majority, female adolescent offenders are a sizeable minority of the overall delinquent population.Further, those females who become involved in delinquent activities appear to be doing so at a younger age, and they are involved in a wide range of criminal activities, including violent offenses.Objective: The

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